In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation

MiR-34a, an important tumor-suppressing microRNA, is downregulated in several types of cancer; loss of its expression has been linked with unfavorable clinical outcomes in non-small-cell lung cancer (NSCLC), among others. MiR-34a represses several key oncogenic proteins, and a synthetic mimic of miR...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Nucleic Acids
Asıl Yazarlar: Cortez, Maria Angelica, Valdecanas, David, Niknam, Sharareh, Peltier, Heidi J, Diao, Lixia, Giri, Uma, Komaki, Ritsuko, Calin, George A, Gomez, Daniel R, Chang, Joe Y, Heymach, John Victor, Bader, Andreas G, Welsh, James William
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014539/
https://ncbi.nlm.nih.gov/pubmed/26670277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.47
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