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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

Mutations in genes that encode components of the phosphatidyl-inositol 3-kinase (PI3-kinase) signaling pathway are common in human cancer. The recent discovery of nonrandom somatic mutations in the PIK3CA gene of many human tumors suggests an oncogenic role for the mutated enzyme. We have determined...

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Bibliografski detalji
Glavni autori: Kang, Sohye, Bader, Andreas G., Vogt, Peter K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545580/
https://ncbi.nlm.nih.gov/pubmed/15647370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408864102
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