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Quantification of Therapeutic miRNA Mimics in Whole Blood from Nonhuman Primates

[Image: see text] MRX34, a microRNA (miRNA)-based therapy for cancer, has recently entered clinical trials as the first clinical candidate in its class. It is a liposomal nanoparticle loaded with a synthetic mimic of the tumor suppressor miRNA miR-34a as the active pharmaceutical ingredient. To unde...

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Bibliografiska uppgifter
Huvudupphovsmän: Kelnar, Kevin, Peltier, Heidi J., Leatherbury, Neil, Stoudemire, Jay, Bader, Andreas G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982984/
https://ncbi.nlm.nih.gov/pubmed/24397447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403044t
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