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An Ebola whole-virus vaccine is protective in nonhuman primates

Zaire ebolavirus is the causative agent of the current outbreak of hemorrhagic fever disease in West Africa. Previously, we showed that a whole Ebola virus (EBOV) vaccine based on a replication-defective EBOV (EBOVΔVP30) protects immunized mice and guinea pigs against lethal challenge with rodent-ad...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Marzi, Andrea, Halfmann, Peter, Hill-Batorski, Lindsay, Feldmann, Friederike, Shupert, W. Lesley, Neumann, Gabriele, Feldmann, Heinz, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565490/
https://ncbi.nlm.nih.gov/pubmed/25814063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa4919
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