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The Cytoprotective Enzyme Heme Oxygenase-1 Suppresses Ebola Virus Replication

Ebola virus (EBOV) is the causative agent of a severe hemorrhagic fever in humans with reported case fatality rates as high as 90%. There are currently no licensed vaccines or antiviral therapeutics to combat EBOV infections. Heme oxygenase-1 (HO-1), an enzyme that catalyzes the rate-limiting step i...

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Detalhes bibliográficos
Main Authors: Hill-Batorski, Lindsay, Halfmann, Peter, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838215/
https://ncbi.nlm.nih.gov/pubmed/24109237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02422-13
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