Replication-Deficient Ebolavirus as a Vaccine Candidate

Ebolavirus causes severe hemorrhagic fever, with case fatality rates as high as 90%. Currently, no licensed vaccine is available against Ebolavirus. We previously generated a replication-deficient, biologically contained Ebolavirus, EbolaΔVP30, which lacks the essential VP30 gene, grows only in cell...

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Détails bibliographiques
Auteurs principaux: Halfmann, Peter, Ebihara, Hideki, Marzi, Andrea, Hatta, Yasuko, Watanabe, Shinji, Suresh, M., Neumann, Gabriele, Feldmann, Heinz, Kawaoka, Yoshihiro
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663241/
https://ncbi.nlm.nih.gov/pubmed/19211761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00074-09
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