Covalent Modulators of the Vacuolar ATPase

Por Chen, Ying-Chu, Backus, Keriann M., Merkulova, Maria, Yang, Christina, Brown, Dennis, Cravatt, Benjamin F., Zhang, Chao
Publicado no J Am Chem Soc (2016)

Global profiling of lysine reactivity and ligandability in the human proteome

Por Hacker, Stephan M., Backus, Keriann M., Lazear, Michael R., Forli, Stefano, Correia, Bruno E., Cravatt, Benjamin F.
Publicado no Nat Chem (2017)

Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells

Por Blewett, Megan M., Xie, Jiji, Zaro, Balyn W., Backus, Keriann M., Altman, Amnon, Teijaro, John R., Cravatt, Benjamin F.
Publicado no Sci Signal (2016)

The Three Mycobacterium tuberculosis Antigen 85 Isoforms Have Unique Substrates and Activities Determined by Non-active Site Regions

Por Backus, Keriann M., Dolan, Michael A., Barry, Conor S., Joe, Maju, McPhie, Peter, Boshoff, Helena I. M., Lowary, Todd L., Davis, Benjamin G., Barry, Clifton E.
Publicado em 2014

A Screen for Protein-Protein Interactions in Live Mycobacteria Reveals a Functional Link Between the Virulence-Associated Lipid Transporter LprG and the Mycolyltransferase Antigen...

Por Touchette, Megan H., Van Vlack, Erik R., Bai, Lu, Kim, Jia, Cognetta, Armand B., Previti, Mary L., Backus, Keriann M., Martin, Dwight W., Cravatt, Benjamin F., Seeliger, Jessica C.
Publicado no ACS Infect Dis (2017)

Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

Por Backus, Keriann M, Boshoff, Helena l, Barry, Conor S, Boutureira, Omar, Patel, Mitul K, D’Hooge, François, Lee, Seung Seo, Via, Laura E, Tahlan, Kapil, Barry, Clifton E, Davis, Benjamin G
Publicado em 2011

Proteome-wide covalent ligand discovery in native biological systems

Por Backus, Keriann M., Correia, Bruno E., Lum, Kenneth M., Forli, Stefano, Horning, Benjamin D., González-Páez, Gonzalo E., Chatterjee, Sandip, Lanning, Bryan R., Teijaro, John R., Olson, Arthur J., Wolan, Dennis W., Cravatt, Benjamin F.
Publicado no Nature (2016)

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

Por Briggs, Kimberly J., Koivunen, Peppi, Cao, Shugeng, Backus, Keriann M., Olenchock, Benjamin A., Patel, Hetalben, Zhang, Qing, Signoretti, Sabina, Gerfen, Gary J., Richardson, Andrea L., Witkiewicz, Agnieszka K., Cravatt, Benjamin F., Clardy, Jon, Kaelin, William G.
Publicado no Cell (2016)

Discovery of reactive microbiota-derived metabolites that inhibit host proteases

Por Guo, Chun-Jun, Chang, Fang-Yuan, Wyche, Thomas P., Backus, Keriann M., Acker, Timothy M., Funabashi, Masanori, Taketani, Mao, Donia, Mohamed S., Nayfach, Stephen, Pollard, Katherine S., Craik, Charles S., Cravatt, Benjamin F., Clardy, Jon, Voigt, Christopher A., Fischbach, Michael A.
Publicado no Cell (2017)

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

Por Bar-Peled, Liron, Kemper, Esther K., Suciu, Radu M., Vinogradova, Ekaterina V., Backus, Keriann M., Horning, Benjamin D., Paul, Thomas A., Ichu, Taka-Aki, Svensson, Robert U., Olucha, Jose, Chang, Max W., Kok, Bernard P., Zhou, Zhu, Ihle, Nathan, Dix, Melissa M., Jiang, Ping, Hayward, Matthew M., Saez, Enrique, Shaw, Reuben J., Cravatt, Benjamin F.
Publicado no Cell (2017)