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Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

The detection of tuberculosis currently relies upon insensitive and unspecific techniques; newer diagnostics would ideally co-opt specific bacterial processes to provide real-time readouts. The trehalose mycolyltransesterase enzymes (antigens 85A, 85B and 85C (Ag85A, Ag85B, Ag85C)) serve as essentia...

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Detalhes bibliográficos
Main Authors: Backus, Keriann M, Boshoff, Helena l, Barry, Conor S, Boutureira, Omar, Patel, Mitul K, D’Hooge, François, Lee, Seung Seo, Via, Laura E, Tahlan, Kapil, Barry, Clifton E, Davis, Benjamin G
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157484/
https://ncbi.nlm.nih.gov/pubmed/21378984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.539
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