Covalent Modulators of the Vacuolar ATPase

The vacuolar H(+) ATPase (V-ATPase) is a complex multi-subunit machine that regulates important cellular processes through controlling acidity of intracellular compartments in eukaryotes. Existing small-molecule modulators of V-ATPase either are restricted to targeting one membranous subunit of V-AT...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Chen, Ying-Chu, Backus, Keriann M., Merkulova, Maria, Yang, Christina, Brown, Dennis, Cravatt, Benjamin F., Zhang, Chao
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274637/
https://ncbi.nlm.nih.gov/pubmed/28010062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12511
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