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A chemoproteomic method for identifying cellular targets of covalent kinase inhibitors
Protein kinases are attractive drug targets for numerous human diseases including cancers, diabetes and neurodegeneration. A number of kinase inhibitors that covalently target a cysteine residue in their target kinases have recently entered use in the cancer clinic. Despite the advantages of covalen...
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| Publicado no: | Genes Cancer |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979588/ https://ncbi.nlm.nih.gov/pubmed/27551330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.106 |
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