Leukemia Inhibitory Factor (LIF)

Por Nicola, Nicos A, Babon, Jeffrey J
Publicado no Cytokine Growth Factor Rev (2015)

Inhibition of IL-6 family cytokines by SOCS3

Por Babon, Jeffrey J., Varghese, Leila N., Nicola, Nicos A.
Publicado em 2014

Chemical cleavage reactions of DNA on solid support: application in mutation detection

Por Bui, Chinh T, Lambrinakos, Andreana, Babon, Jeffrey J, Cotton, Richard GH
Publicado em 2003

Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: Identification of the active components and JAK2 and gp130 as substrates

Por Kershaw, Nadia J., Laktyushin, Artem, Nicola, Nicos A., Babon, Jeffrey J.
Publicado em 2014

Suppression of Cytokine Signaling: the SOCS perspective

Por Linossi, Edmond M., Babon, Jeffrey J., Hilton, Douglas J., Nicholson, Sandra E.
Publicado em 2013

The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression

Por Babon, Jeffrey J., Sabo, Jennifer K., Zhang, Jian-Guo, Nicola, Nicos A., Norton, Raymond S.
Publicado em 2009

Regulation of Janus Kinases by SOCS proteins

Por Kershaw, Nadia J., Murphy, James M., Lucet, Isabelle S., Nicola, Nicos A., Babon, Jeffrey J.
Publicado em 2013

The molecular regulation of Janus kinase (JAK) activation

Por Babon, Jeffrey J., Lucet, Isabelle S, Murphy, James M, Nicola, Nicos A, Varghese, Leila N
Publicado em 2014

Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity

Por D'Cruz, Akshay A, Babon, Jeffrey J, Norton, Raymond S, Nicola, Nicos A, Nicholson, Sandra E
Publicado em 2013

Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases

Por Muniz, João R.C., Guo, Kunde, Kershaw, Nadia J., Ayinampudi, Vikram, von Delft, Frank, Babon, Jeffrey J., Bullock, Alex N.
Publicado em 2013

Dynamics of the SPRY domain–containing SOCS box protein 2: Flexibility of key functional loops

Por Yao, Shenggen, Liu, Ming S., Masters, Seth L., Zhang, Jian-Guo, Babon, Jeffrey J., Nicola, Nicos A., Nicholson, Sandra E., Norton, Raymond S.
Publicado em 2006

The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase

Por Babon, Jeffrey J., Sabo, Jennifer K., Soetopo, Alfreda, Yao, Shenggen, Bailey, Michael F., Zhang, Jian-Guo, Nicola, Nicos A., Norton, Raymond S.
Publicado em 2008

Structure and Sodium Channel Activity of an Excitatory I(1)-Superfamily Conotoxin

Por Buczek, Olga, Wei, Daxiu, Babon, Jeffrey J., Yang, Xiaodong, Fiedler, Brian, Chen, Ping, Yoshikami, Doju, Olivera, Baldomero M., Bulaj, Grzegorz, Norton, Raymond S.
Publicado em 2007

Suppression of Cytokine Signalling by SOCS3: Characterisation of the mode of inhibition and the basis of its specificity

Por Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.
Publicado em 2012

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling

Por D'Cruz, Akshay A., Kershaw, Nadia J., Chiang, Jessica J., Wang, May K., Nicola, Nicos A., Babon, Jeffrey J., Gack, Michaela U., Nicholson, Sandra E.
Publicado em 2013

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

Por Kershaw, Nadia J., Murphy, James M., Liau, Nicholas P.D., Varghese, Leila N., Laktyushin, Artem, Whitlock, Eden L., Lucet, Isabelle S., Nicola, Nicos A., Babon, Jeffrey J.
Publicado em 2013

Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses

Por Varghese, Leila N., Ungureanu, Daniela, Liau, Nicholas P. D., Young, Samuel N., Laktyushin, Artem, Hammaren, Henrik, Lucet, Isabelle S., Nicola, Nicos A., Silvennoinen, Olli, Babon, Jeffrey J., Murphy, James M.
Publicado em 2014

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA

Por Hands-Taylor, Katherine L. D., Martino, Luigi, Tata, Renée, Babon, Jeffrey J., Bui, Tam T., Drake, Alex F., Beavil, Rebecca L., Pruijn, Ger J. M., Brown, Paul R., Conte, Maria R.
Publicado em 2010

Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1

Por Linossi, Edmond M., Chandrashekaran, Indu R., Kolesnik, Tatiana B., Murphy, James M., Webb, Andrew I., Willson, Tracy A., Kedzierski, Lukasz, Bullock, Alex N., Babon, Jeffrey J., Norton, Raymond S., Nicola, Nicos A., Nicholson, Sandra E.
Publicado em 2013

The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

Por Kuang, Zhihe, Lewis, Rowena S., Curtis, Joan M., Zhan, Yifan, Saunders, Bernadette M., Babon, Jeffrey J., Kolesnik, Tatiana B., Low, Andrew, Masters, Seth L., Willson, Tracy A., Kedzierski, Lukasz, Yao, Shenggen, Handman, Emanuela, Norton, Raymond S., Nicholson, Sandra E.
Publicado em 2010