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Regulation of Janus Kinases by SOCS proteins
Janus Kinases (JAKs) are essential mediators of almost all biological signalling events initiated by haemopoietic and immune cytokines. However, aberrant and/or prolonged JAK- induced signalling is detrimental and can give rise to a number of inflammatory and proliferative pathologies. For this reas...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773493/ https://ncbi.nlm.nih.gov/pubmed/23863176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130077 |
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