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Regulation of Janus Kinases by SOCS proteins

Janus Kinases (JAKs) are essential mediators of almost all biological signalling events initiated by haemopoietic and immune cytokines. However, aberrant and/or prolonged JAK- induced signalling is detrimental and can give rise to a number of inflammatory and proliferative pathologies. For this reas...

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Bibliografische gegevens
Hoofdauteurs: Kershaw, Nadia J., Murphy, James M., Lucet, Isabelle S., Nicola, Nicos A., Babon, Jeffrey J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773493/
https://ncbi.nlm.nih.gov/pubmed/23863176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130077
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