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The molecular basis of JAK/STAT inhibition by SOCS1
The SOCS family of proteins are negative-feedback inhibitors of signalling induced by cytokines that act via the JAK/STAT pathway. SOCS proteins can act as ubiquitin ligases by recruiting Cullin5 to ubiquitinate signalling components; however, SOCS1, the most potent member of the family, can also in...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908791/ https://ncbi.nlm.nih.gov/pubmed/29674694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04013-1 |
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