Decreased mitochondrial tRNALys steady-state levels and aminoacylation are associated with the pathogenic G8313A mitochondrial DNA mutation.

Por Bacman, Sandra R, Atencio, David P, Moraes, Carlos T
Publicado em 2003

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks

Por Bacman, Sandra R., Williams, Sion L., Moraes, Carlos T.
Publicado em 2009

Modulating mtDNA heteroplasmy by mitochondria-targeted restriction endonucleases in a ‘differential multiple cleavage-site’ model

Por Bacman, SR, Williams, SL, Hernandez, D, Moraes, CT
Publicado em 2007

Manipulating mitochondrial genomes in the clinic: playing by different rules

Por Moraes, Carlos T., Bacman, Sandra R., Williams, Sion L.
Publicado no Trends Cell Biol (2014)

Negative inotropic activity of antilaminin IgG: participation of cholinergic mechanisms.

Por Bacman, S., Borda, E., Denduchis, B., Lustig, L., Sterin-Borda, L.
Publicado em 1989

Participation of cytoskeleton in the effect of antilaminin IgG on cardiac cholinoceptors.

Por Bacman, S., Borda, E., Denduchis, B., Lustig, L., Sterin-Borda, L.
Publicado em 1994

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease

Por Bacman, Sandra R., Williams, Sion L., Garcia, Sofia, Moraes, Carlos T.
Publicado em 2010

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria targeted restriction endonuclease

Por Bacman, Sandra R., Williams, Sion L., Duan, Dongsheng, Moraes, Carlos T.
Publicado em 2011

The Use of Mitochondria-Targeted Endonucleases to Manipulate mtDNA

Por Bacman, Sandra R., Williams, Sion L., Pinto, Milena, Moraes, Carlos T.
Publicado no Methods Enzymol (2014)

TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in co...

Por Bacman, David, Merkel, Susanne, Croner, Roland, Papadopoulos, Thomas, Brueckl, Wolfgang, Dimmler, Arno
Publicado em 2007

Specific elimination of mutant mitochondrial genomes in patient–derived cells by mitoTALENs

Por Bacman, Sandra R., Williams, Siôn L., Pinto, Milena, Peralta, Susana, Moraes, Carlos T.
Publicado em 2013

Circulating antibodies against rat parotid gland M(3) muscarinic receptors in primary Sjögren's syndrome

Por BACMAN, S, STERIN-BORDA, L, JOSÉ CAMUSSO, J, ARANA, R, HUBSCHER, O, BORDA, E
Publicado em 1996

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases

Por Hashimoto, Masami, Bacman, Sandra R, Peralta, Susana, Falk, Marni J, Chomyn, Anne, Chan, David C, Williams, Sion L, Moraes, Carlos T
Publicado no Mol Ther (2015)

Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner

Por Pinto, Milena, Pickrell, Alicia M, Wang, Xiao, Bacman, Sandra R, Yu, Aixin, Hida, Aline, Dillon, Lloye M, Morton, Paul D, Malek, Thomas R, Williams, Siôn L, Moraes, Carlos T
Publicado no Cell Death Differ (2017)

Selective elimination of mitochondrial mutations in the germline by genome editing

Por Reddy, Pradeep, Ocampo, Alejandro, Suzuki, Keiichiro, Luo, Jinping, Bacman, Sandra R., Williams, Sion L., Sugawara, Atsushi, Okamura, Daiji, Tsunekawa, Yuji, Wu, Jun, Lam, David, Xiong, Xiong, Montserrat, Nuria, Esteban, Concepcion Rodriguez, Liu, Guang-Hui, Sancho-Martinez, Ignacio, Manau, Dolors, Civico, Salva, Cardellach, Francesc, O’Callaghan, Maria del Mar, Campistol, Jaime, Zhao, Huimin, Campistol, Josep Maria, Moraes, Carlos T., Belmonte, Juan Carlos Izpisua
Publicado no Cell (2015)