Insights into the composition of stroke thrombi: heterogeneity and distinct clot areas impact treatment

par Xu, Rui-Gang, Ariëns, Robert A. S.
Publié dans Haematologica (2020)

Mechanisms of thrombosis and cardiovascular complications in COVID-19

par Page, Eden M., Ariëns, Robert A.S.
Publié dans Thromb Res (2021)

Clot Structure and Fibrinolysis in Thrombosis and Hemostasis

par Bagoly, Zsuzsa, Ariëns, Robert A. S., Rijken, Dingeman C., Pieters, Marlien, Wolberg, Alisa S.
Publié dans Biomed Res Int (2017)

α−α Cross-Links Increase Fibrin Fiber Elasticity and Stiffness

par Helms, Christine C., Ariëns, Robert A.S., Uitte de Willige, S., Standeven, Kristina F., Guthold, Martin
Publié 2012

Recurrent venous thromboembolism patients form clots with lower elastic modulus than those formed by patients with non‐recurrent disease

par Baker, Stephen R., Zabczyk, Michal, Macrae, Fraser L., Duval, Cédric, Undas, Anetta, Ariëns, Robert A. S.
Publié dans J Thromb Haemost (2019)

Effect of anticoagulants on fibrin clot structure: A comparison between vitamin K antagonists and factor Xa inhibitors

par Gauer, Julia S., Riva, Nicoletta, Page, Eden M., Philippou, Helen, Makris, Michael, Gatt, Alex, Ariëns, Robert A. S.
Publié dans Res Pract Thromb Haemost (2020)

Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII

par Mouapi, Kelly Njine, Bell, Jacob D., Smith, Kerrie A., Ariëns, Robert A. S., Philippou, Helen, Maurer, Muriel C.
Publié dans Blood (2016)

Common FXIII and Fibrinogen Polymorphisms in Abdominal Aortic Aneurysms

par Macrae, Fraser L., Lee Evans, Hannah, Bridge, Katherine I., Johnson, Anne, Scott, D. Julian A., Ariëns, Robert A. S.
Publié dans PLoS One (2014)

Polyphosphate Delays Fibrin Polymerisation and Alters the Mechanical Properties of the Fibrin Network

par Whyte, Claire S., Chernysh, Irina N., Domingues, Marco M., Connell, Simon, Weisel, John W., Ariens, Robert A. S., Mutch, Nicola J.
Publié dans Thromb Haemost (2016)

Fibrinogen αC‐regions are not directly involved in fibrin polymerization as evidenced by a “Double‐Detroit” recombinant fibrinogen mutant and knobs‐mimic peptides

par Duval, Cédric, Profumo, Aldo, Aprile, Anna, Salis, Annalisa, Millo, Enrico, Damonte, Gianluca, Gauer, Julia S., Ariëns, Robert A. S., Rocco, Mattia
Publié dans J Thromb Haemost (2020)

Proteolytic and Nonproteolytic Activation Mechanisms Result in Conformationally and Functionally Different Forms of Coagulation Factor XIII A

par Anokhin, Boris A., Dean, William L., Smith, Kerrie A., Flick, Matthew J., Ariëns, Robert A.S., Philippou, Helen, Maurer, Muriel C.
Publié dans FEBS J (2019)

On the localization of the cleavage site in human alpha‐2‐antiplasmin, involved in the generation of the non‐plasminogen binding form

par Abdul, Shiraazkhan, Dekkers, Dick H. W., Ariëns, Robert A. S., Leebeek, Frank W. G., Rijken, Dingeman C., Uitte de Willige, Shirley
Publié dans J Thromb Haemost (2020)

Nanoscale Probing Reveals that Reduced Stiffness of Clots from Fibrinogen Lacking 42 N-Terminal Bβ-Chain Residues Is Due to the Formation of Abnormal Oligomers

par Abou-Saleh, Radwa H., Connell, Simon D., Harrand, Robert, Ajjan, Ramzi A., Mosesson, Michael W., Smith, D. Alastair M., Grant, Peter J., Ariëns, Robert A.S.
Publié 2009

GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region

par Xu, Rui-Gang, Gauer, Julia S., Baker, Stephen R., Slater, Alexandre, Martin, Eleyna M., McPherson, Helen R., Duval, Cédric, Manfield, Iain W., Bonna, Arkadiusz M., Watson, Steve P., Ariëns, Robert A.S.
Publié dans Arterioscler Thromb Vasc Biol (2021)

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

par Byrnes, James R., Duval, Cédric, Wang, Yiming, Hansen, Caroline E., Ahn, Byungwook, Mooberry, Micah J., Clark, Martha A., Johnsen, Jill M., Lord, Susan T., Lam, Wilbur A., Meijers, Joost C. M., Ni, Heyu, Ariëns, Robert A. S., Wolberg, Alisa S.
Publié dans Blood (2015)

Fibrin and D-dimer bind to monomeric GPVI

par Onselaer, Marie-Blanche, Hardy, Alexander T., Wilson, Clare, Sanchez, Ximena, Babar, Amir K., Miller, Jeanette L. C., Watson, Callum N., Watson, Stephanie K., Bonna, Arkadiusz, Philippou, Helen, Herr, Andrew B., Mezzano, Diego, Ariëns, Robert A. S., Watson, Steve P.
Publié dans Blood Adv (2017)

A fibrin biofilm covers blood clots and protects from microbial invasion

par Macrae, Fraser L., Duval, Cédric, Papareddy, Praveen, Baker, Stephen R., Yuldasheva, Nadira, Kearney, Katherine J., McPherson, Helen R., Asquith, Nathan, Konings, Joke, Casini, Alessandro, Degen, Jay L., Connell, Simon D., Philippou, Helen, Wolberg, Alisa S., Herwald, Heiko, Ariëns, Robert A.S.
Publié dans J Clin Invest (2018)

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

par Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E. J., Naseem, Khalid M., Ariens, Robert A. S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publié dans Blood (2019)

Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi

par Duval, Cédric, Baranauskas, Adomas, Feller, Tímea, Ali, Majid, Cheah, Lih T., Yuldasheva, Nadira Y., Baker, Stephen R., McPherson, Helen R., Raslan, Zaher, Bailey, Marc A., Cubbon, Richard M., Connell, Simon D., Ajjan, Ramzi A., Philippou, Helen, Naseem, Khalid M., Ridger, Victoria C., Ariëns, Robert A. S.
Publié dans Proc Natl Acad Sci U S A (2021)

A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm

par Jones, Gregory T., Bown, Matthew J., Gretarsdottir, Solveig, Romaine, Simon P.R., Helgadottir, Anna, Yu, Grace, Tromp, Gerard, Norman, Paul E., Jin, Cao, Baas, Annette F., Blankensteijn, Jan D., Kullo, Iftikhar J., Phillips, L. Victoria, Williams, Michael J.A., Topless, Ruth, Merriman, Tony R., Vasudevan, Thodor M., Lewis, David R., Blair, Ross D., Hill, Andrew A., Sayers, Robert D., Powell, Janet T., Deloukas, Panagiotis, Thorleifsson, Gudmar, Matthiasson, Stefan E., Thorsteinsdottir, Unnur, Golledge, Jonathan, Ariëns, Robert A., Johnson, Anne, Sohrabi, Soroush, Scott, D. Julian, Carey, David J., Erdman, Robert, Elmore, James R., Kuivaniemi, Helena, Samani, Nilesh J., Stefansson, Kari, van Rij, Andre M.
Publié 2013