Insights into the composition of stroke thrombi: heterogeneity and distinct clot areas impact treatment

por Xu, Rui-Gang, Ariëns, Robert A. S.
Publicado no Haematologica (2020)

Mechanisms of thrombosis and cardiovascular complications in COVID-19

por Page, Eden M., Ariëns, Robert A.S.
Publicado no Thromb Res (2021)

Clot Structure and Fibrinolysis in Thrombosis and Hemostasis

por Bagoly, Zsuzsa, Ariëns, Robert A. S., Rijken, Dingeman C., Pieters, Marlien, Wolberg, Alisa S.
Publicado no Biomed Res Int (2017)

α−α Cross-Links Increase Fibrin Fiber Elasticity and Stiffness

por Helms, Christine C., Ariëns, Robert A.S., Uitte de Willige, S., Standeven, Kristina F., Guthold, Martin
Publicado em 2012

Recurrent venous thromboembolism patients form clots with lower elastic modulus than those formed by patients with non‐recurrent disease

por Baker, Stephen R., Zabczyk, Michal, Macrae, Fraser L., Duval, Cédric, Undas, Anetta, Ariëns, Robert A. S.
Publicado no J Thromb Haemost (2019)

Effect of anticoagulants on fibrin clot structure: A comparison between vitamin K antagonists and factor Xa inhibitors

por Gauer, Julia S., Riva, Nicoletta, Page, Eden M., Philippou, Helen, Makris, Michael, Gatt, Alex, Ariëns, Robert A. S.
Publicado no Res Pract Thromb Haemost (2020)

Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII

por Mouapi, Kelly Njine, Bell, Jacob D., Smith, Kerrie A., Ariëns, Robert A. S., Philippou, Helen, Maurer, Muriel C.
Publicado no Blood (2016)

Common FXIII and Fibrinogen Polymorphisms in Abdominal Aortic Aneurysms

por Macrae, Fraser L., Lee Evans, Hannah, Bridge, Katherine I., Johnson, Anne, Scott, D. Julian A., Ariëns, Robert A. S.
Publicado no PLoS One (2014)

Polyphosphate Delays Fibrin Polymerisation and Alters the Mechanical Properties of the Fibrin Network

por Whyte, Claire S., Chernysh, Irina N., Domingues, Marco M., Connell, Simon, Weisel, John W., Ariens, Robert A. S., Mutch, Nicola J.
Publicado no Thromb Haemost (2016)

Fibrinogen αC‐regions are not directly involved in fibrin polymerization as evidenced by a “Double‐Detroit” recombinant fibrinogen mutant and knobs‐mimic peptides

por Duval, Cédric, Profumo, Aldo, Aprile, Anna, Salis, Annalisa, Millo, Enrico, Damonte, Gianluca, Gauer, Julia S., Ariëns, Robert A. S., Rocco, Mattia
Publicado no J Thromb Haemost (2020)

Proteolytic and Nonproteolytic Activation Mechanisms Result in Conformationally and Functionally Different Forms of Coagulation Factor XIII A

por Anokhin, Boris A., Dean, William L., Smith, Kerrie A., Flick, Matthew J., Ariëns, Robert A.S., Philippou, Helen, Maurer, Muriel C.
Publicado no FEBS J (2019)

On the localization of the cleavage site in human alpha‐2‐antiplasmin, involved in the generation of the non‐plasminogen binding form

por Abdul, Shiraazkhan, Dekkers, Dick H. W., Ariëns, Robert A. S., Leebeek, Frank W. G., Rijken, Dingeman C., Uitte de Willige, Shirley
Publicado no J Thromb Haemost (2020)

Nanoscale Probing Reveals that Reduced Stiffness of Clots from Fibrinogen Lacking 42 N-Terminal Bβ-Chain Residues Is Due to the Formation of Abnormal Oligomers

por Abou-Saleh, Radwa H., Connell, Simon D., Harrand, Robert, Ajjan, Ramzi A., Mosesson, Michael W., Smith, D. Alastair M., Grant, Peter J., Ariëns, Robert A.S.
Publicado em 2009

GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region

por Xu, Rui-Gang, Gauer, Julia S., Baker, Stephen R., Slater, Alexandre, Martin, Eleyna M., McPherson, Helen R., Duval, Cédric, Manfield, Iain W., Bonna, Arkadiusz M., Watson, Steve P., Ariëns, Robert A.S.
Publicado no Arterioscler Thromb Vasc Biol (2021)

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

por Byrnes, James R., Duval, Cédric, Wang, Yiming, Hansen, Caroline E., Ahn, Byungwook, Mooberry, Micah J., Clark, Martha A., Johnsen, Jill M., Lord, Susan T., Lam, Wilbur A., Meijers, Joost C. M., Ni, Heyu, Ariëns, Robert A. S., Wolberg, Alisa S.
Publicado no Blood (2015)

Fibrin and D-dimer bind to monomeric GPVI

por Onselaer, Marie-Blanche, Hardy, Alexander T., Wilson, Clare, Sanchez, Ximena, Babar, Amir K., Miller, Jeanette L. C., Watson, Callum N., Watson, Stephanie K., Bonna, Arkadiusz, Philippou, Helen, Herr, Andrew B., Mezzano, Diego, Ariëns, Robert A. S., Watson, Steve P.
Publicado no Blood Adv (2017)

A fibrin biofilm covers blood clots and protects from microbial invasion

por Macrae, Fraser L., Duval, Cédric, Papareddy, Praveen, Baker, Stephen R., Yuldasheva, Nadira, Kearney, Katherine J., McPherson, Helen R., Asquith, Nathan, Konings, Joke, Casini, Alessandro, Degen, Jay L., Connell, Simon D., Philippou, Helen, Wolberg, Alisa S., Herwald, Heiko, Ariëns, Robert A.S.
Publicado no J Clin Invest (2018)

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

por Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E. J., Naseem, Khalid M., Ariens, Robert A. S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publicado no Blood (2019)

Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi

por Duval, Cédric, Baranauskas, Adomas, Feller, Tímea, Ali, Majid, Cheah, Lih T., Yuldasheva, Nadira Y., Baker, Stephen R., McPherson, Helen R., Raslan, Zaher, Bailey, Marc A., Cubbon, Richard M., Connell, Simon D., Ajjan, Ramzi A., Philippou, Helen, Naseem, Khalid M., Ridger, Victoria C., Ariëns, Robert A. S.
Publicado no Proc Natl Acad Sci U S A (2021)

A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm

por Jones, Gregory T., Bown, Matthew J., Gretarsdottir, Solveig, Romaine, Simon P.R., Helgadottir, Anna, Yu, Grace, Tromp, Gerard, Norman, Paul E., Jin, Cao, Baas, Annette F., Blankensteijn, Jan D., Kullo, Iftikhar J., Phillips, L. Victoria, Williams, Michael J.A., Topless, Ruth, Merriman, Tony R., Vasudevan, Thodor M., Lewis, David R., Blair, Ross D., Hill, Andrew A., Sayers, Robert D., Powell, Janet T., Deloukas, Panagiotis, Thorleifsson, Gudmar, Matthiasson, Stefan E., Thorsteinsdottir, Unnur, Golledge, Jonathan, Ariëns, Robert A., Johnson, Anne, Sohrabi, Soroush, Scott, D. Julian, Carey, David J., Erdman, Robert, Elmore, James R., Kuivaniemi, Helena, Samani, Nilesh J., Stefansson, Kari, van Rij, Andre M.
Publicado em 2013