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α−α Cross-Links Increase Fibrin Fiber Elasticity and Stiffness

Fibrin fibers, which are ∼100 nm in diameter, are the major structural component of a blood clot. The mechanical properties of single fibrin fibers determine the behavior of a blood clot and, thus, have a critical influence on heart attacks, strokes, and embolisms. Cross-linking is thought to fortif...

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Autors principals: Helms, Christine C., Ariëns, Robert A.S., Uitte de Willige, S., Standeven, Kristina F., Guthold, Martin
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250683/
https://ncbi.nlm.nih.gov/pubmed/22225811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4016
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