Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Bleeding complications secondary to surgery, trauma, or coagulation disorders are important causes of morbidity and mortality. Although fibrin sealants are considered to minimize blood loss, this is not widely adopted because of its high cost and/or risk for infection. We present a novel methodology...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E. J., Naseem, Khalid M., Ariens, Robert A. S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474728/
https://ncbi.nlm.nih.gov/pubmed/30545831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-856195
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