Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Bleeding complications secondary to surgery, trauma, or coagulation disorders are important causes of morbidity and mortality. Although fibrin sealants are considered to minimize blood loss, this is not widely adopted because of its high cost and/or risk for infection. We present a novel methodology...

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Vydáno v:Blood
Hlavní autoři: Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E. J., Naseem, Khalid M., Ariens, Robert A. S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474728/
https://ncbi.nlm.nih.gov/pubmed/30545831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-856195
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