Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level

od Pearce, Larry V., Ann, Jihyae, Blumberg, Peter M., Lee, Jeewoo
Wydane w Biomol Ther (Seoul) (2019)

An Aminopropyl Carbazole Derivative Induces Neurogenesis by Increasing Final Cell Division in Neural Stem Cells

od Shin, Jae-Yeon, Kong, Sun-Young, Yoon, Hye Jin, Ann, Jihyae, Lee, Jeewoo, Kim, Hyun-Jung
Wydane w Biomol Ther (Seoul) (2015)

Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes

od Cooke, Mariana, Casado-Medrano, Victoria, Ann, Jihyae, Lee, Jeewoo, Blumberg, Peter M., Abba, Martin C., Kazanietz, Marcelo G.
Wydane w Sci Rep (2019)

Functional Group-Dependent Induction of Astrocytogenesis and Neurogenesis by Flavone Derivatives

od Lee, Ha-Rim, Kang, Jin Mi, Kim, Young Min, Kim, Sagang, Ann, Jihyae, Lee, Jeewoo, Kim, Hyun-Jung
Wydane w Biomolecules (2019)

Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones)

od Ann, Jihyae, Yoon, Suyoung, Baek, Jisoo, Kim, Da Hye, Lewin, Nancy E., Hill, Colin S., Blumberg, Peter M., Lee, Jeewoo
Wydane w Eur J Med Chem (2014)

Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1)

od Pearce, Larry V., Ann, Jihyae, Jung, Aeran, Thorat, Shivaji A., Herold, Brienna K. A., Habtemichael, Amelework D., Blumberg, Peter M., Lee, Jeewoo
Wydane w J Med Chem (2017)

Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes

od Cooke, Mariana, Zhou, Xiaoling, Casado-Medrano, Victoria, Lopez-Haber, Cynthia, Baker, Martin J., Garg, Rachana, Ann, Jihyae, Lee, Jeewoo, Blumberg, Peter M., Kazanietz, Marcelo G.
Wydane w J Biol Chem (2018)

Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

od Lee, Sunho, Kim, Changhoon, Ann, Jihyae, Thorat, Shivaji A., Kim, Eunhye, Park, Jongmi, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Wydane w Bioorg Med Chem Lett (2017)

A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer

od Park, Jung Min, Kim, Yoon-Jae, Park, Soeun, Park, Minsu, Farrand, Lee, Nguyen, Cong-Truong, Ann, Jihyae, Nam, Gibeom, Park, Hyun-Ju, Lee, Jeewoo, Kim, Ji Young, Seo, Jae Hong
Wydane w Mol Cancer (2020)

The carbonate analogues of 5′-halogenated resiniferatoxin as TRPV1 ligands

od Lim, Kwang Su, Lee, Hobin, Kim, Sung Eun, Ha, Tae-Hwan, Ann, Jihyae, Son, Karam, Choi, Sun, Sun, Wei, Pearce, Larry V., DeAndrea-Lazarus, Ian A., Blumberg, Peter M., Lee, Jeewoo
Wydane w Eur J Med Chem (2013)

α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists

od Kim, Ho Shin, Jin, Mi-Kyoung, Kang, Sang-Uk, Lim, Ju-Ok, Tran, Phuong-Thao, Hoang, Van-Hai, Ann, Jihyae, Ha, Tae-Hwan, Pearce, Larry V., Pavlyukovets, Vladimir A., Blumberg, Peter M., Lee, Jeewoo
Wydane w Bioorg Med Chem Lett (2014)

t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

od Lee, Sunho, Kang, Dong Wook, Ryu, HyungChul, Kim, Changhoon, Ann, Jihyae, Lee, Hobin, Kim, Eunhye, Hong, Sunhye, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Wydane w Bioorg Med Chem (2017)

Development of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer

od Hyun, Seung Yeob, Le, Huong Thuy, Nguyen, Cong-Truong, Yong, Young-Sik, Boo, Hye-Jin, Lee, Ho Jin, Lee, Ji-Sun, Min, Hye-Young, Ann, Jihyae, Chen, Jie, Park, Hyun-Ju, Lee, Jeewoo, Lee, Ho-Young
Wydane w Sci Rep (2018)

Discovery of Dual-acting Opioid Ligand and TRPV1 Antagonists as Novel Therapeutic Agents for Pain

od Lee, Hobin, Ahn, Songyeon, Ann, Jihyae, Ha, Heejin, Yoo, Young Dong, Kim, Young Ho, Hwang, Ji-Young, Hur, Kwang-Hyun, Jang, Choon-Gon, Pearce, Larry V., Esch, Timothy E., Lewin, Nancy E., Blumberg, Peter M., Lee, Jeewoo
Wydane w Eur J Med Chem (2019)

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

od Ann, Jihyae, Jung, Aeran, Kim, Mi-Yeon, Kim, Hyuk-Min, Ryu, HyungChul, Kim, Sunjoo, Kang, Dong Wook, Hong, Sunhye, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Wydane w Bioorg Med Chem (2015)

2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region

od Thorat, Shivaji A., Kang, Dong Wook, Ryu, HyungChul, Kim, Myeong Seop, Kim, Ho Shin, Ann, Jihyae, Ha, Taehwan, Kim, Sung-Eun, Son, Karam, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo
Wydane w Eur J Med Chem (2013)

TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl) propanamides

od Ha, Tae-Hwan, Ryu, HyungChul, Kim, Sung-Eun, Kim, Ho Shin, Ann, Jihyae, Tran, Phuong-Thao, Hoang, Van-Hai, Son, Karam, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Wydane w Bioorg Med Chem (2013)

α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists

od Tran, Phuong-Thao, Kim, Ho Shin, Ann, Jihyae, Kim, Sung-Eun, Kim, Changhoon, Hong, Mannkyu, Hoang, Van-Hai, Ngo, Van T. H., Hong, Sunhye, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Wydane w Bioorg Med Chem Lett (2015)

Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template

od Ann, Jihyae, Sun, Wei, Zhou, Xing, Jung, Aeran, Baek, Jisoo, Lee, Sunho, Kim, Changhoon, Yoon, Suyoung, Hong, Sunhye, Choi, Sun, Turcios, Noe A., Herold, Brienna K. A., Esch, Timothy E., Lewin, Nancy E., Abramovitz, Adelle, Pearce, Larry V., Blumberg, Peter M., Lee, Jeewoo
Wydane w Bioorg Med Chem Lett (2016)

Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

od Ryu, HyungChul, Seo, Sejin, Lee, Jee-Young, Ha, Tae-Hwan, Lee, Sunho, Jung, Aeran, Ann, Jihyae, Kim, Sung-Eun, Yoon, Suyoung, Hong, Mannkyu, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Schiene, Klaus, Stockhausen, Hannelore, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Wydane w Eur J Med Chem (2015)