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Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones)
DAG-lactones afford a synthetically accessible, high affinity platform for probing structure activity relationships at the C1 regulatory domain of protein kinase C (PKC). Given the central role of PKC isoforms in cellular signaling, along with their differential biological activities, a critical obj...
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| Publicado no: | Eur J Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957255/ https://ncbi.nlm.nih.gov/pubmed/25437619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.11.025 |
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