PROTEIN KINASE C IN CANCER: THE TOP FIVE UNANSWERED QUESTIONS

Por Cooke, Mariana, Magimaidas, Andrew, Casado-Medrano, Victoria, Kazanietz, Marcelo G.
Publicado no Mol Carcinog (2017)

PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells

Por Cooke, Mariana, Baker, Martin J., Kazanietz, Marcelo G., Casado-Medrano, Victoria
Publicado no Small GTPases (2019)

Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α

Por Lopez-Haber, Cynthia, Barrio-Real, Laura, Casado-Medrano, Victoria, Kazanietz, Marcelo G.
Publicado no Mol Cell Biol (2016)

The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses

Por Kazanietz, Marcelo G., Barrio-Real, Laura, Casado-Medrano, Victoria, Baker, Martin J., Lopez-Haber, Cynthia
Publicado no Small GTPases (2016)

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression

Por Casado-Medrano, Victoria, Barrio-Real, Laura, García-Rostán, Ginesa, Baumann, Matti, Rocks, Oliver, Caloca, María J.
Publicado no Oncotarget (2016)

DISTINCTIVE REQUIREMENT OF PKCε IN THE CONTROL OF Rho GTPases IN EPITHELIAL AND MESENCHYMALLY-TRANSFORMED LUNG CANCER CELLS

Por Casado-Medrano, Victoria, Barrio-Real, Laura, Wang, Anita, Cooke, Mariana, Lopez-Haber, Cynthia, Kazanietz, Marcelo G.
Publicado no Oncogene (2019)

Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes

Por Cooke, Mariana, Casado-Medrano, Victoria, Ann, Jihyae, Lee, Jeewoo, Blumberg, Peter M., Abba, Martin C., Kazanietz, Marcelo G.
Publicado no Sci Rep (2019)

THE ROLE OF RAC IN TUMOUR SUSCEPTIBILITY AND DISEASE PROGRESSION: FROM BIOCHEMISTRY TO THE CLINIC

Por Casado-Medrano, Victoria, Baker, Martin J., Lopez-Haber, Cynthia, Cooke, Mariana, Wang, Shaofei, Caloca, Maria J., Kazanietz, Marcelo G.
Publicado no Biochem Soc Trans (2018)

P-Rex1 is dispensable for Erk activation and mitogenesis in breast cancer

Por Barrio-Real, Laura, Lopez-Haber, Cynthia, Casado-Medrano, Victoria, Goglia, Alexander G., Toettcher, Jared E., Caloca, Maria J., Kazanietz, Marcelo G.
Publicado no Oncotarget (2018)

Identification of a truncated β1-chimaerin variant that inactivates nuclear Rac1

Por Casado-Medrano, Victoria, Barrio-Real, Laura, Gutiérrez-Miranda, Laura, González-Sarmiento, Rogelio, Velasco, Eladio A., Kazanietz, Marcelo G., Caloca, María J.
Publicado no J Biol Chem (2020)

Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

Por Guedan, Sonia, Madar, Aviv, Casado-Medrano, Victoria, Shaw, Carolyn, Wing, Anna, Liu, Fang, Young, Regina M., June, Carl H., Posey, Avery D.
Publicado no J Clin Invest (2020)

Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes

Por Cooke, Mariana, Zhou, Xiaoling, Casado-Medrano, Victoria, Lopez-Haber, Cynthia, Baker, Martin J., Garg, Rachana, Ann, Jihyae, Lee, Jeewoo, Blumberg, Peter M., Kazanietz, Marcelo G.
Publicado no J Biol Chem (2018)

Interaction modulation through arrays of clustered methyl-arginine protein modifications

Por Woodsmith, Jonathan, Casado-Medrano, Victoria, Benlasfer, Nouhad, Eccles, Rebecca L, Hutten, Saskia, Heine, Christian L, Thormann, Verena, Abou-Ajram, Claudia, Rocks, Oliver, Dormann, Dorothee, Stelzl, Ulrich
Publicado no Life Sci Alliance (2018)

CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

Por Rodriguez-Garcia, Alba, Lynn, Rachel C., Poussin, Mathilde, Eiva, Monika A., Shaw, Lauren C., O’Connor, Roddy S., Minutolo, Nicholas G., Casado-Medrano, Victoria, Lopez, Gonzalo, Matsuyama, Takami, Powell, Daniel J.
Publicado no Nat Commun (2021)

Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

Por Guedan, Sonia, Posey, Avery D., Shaw, Carolyn, Wing, Anna, Da, Tong, Patel, Prachi R., McGettigan, Shannon E., Casado-Medrano, Victoria, Kawalekar, Omkar U., Uribe-Herranz, Mireia, Song, Decheng, Melenhorst, J. Joseph, Lacey, Simon F., Scholler, John, Keith, Brian, Young, Regina M., June, Carl H.
Publicado no JCI Insight (2018)