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DISTINCTIVE REQUIREMENT OF PKCε IN THE CONTROL OF Rho GTPases IN EPITHELIAL AND MESENCHYMALLY-TRANSFORMED LUNG CANCER CELLS
Diacylglycerol (DAG)/phorbol ester-regulated protein kinase C (PKC) isozymes have been widely linked to tumor promotion and the development of a metastatic phenotype. PKCε, an oncogenic member of the PKC family, is abnormally overexpressed in lung cancer and other cancer types. This kinase plays sig...
Enregistré dans:
| Publié dans: | Oncogene |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609469/ https://ncbi.nlm.nih.gov/pubmed/30923343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0796-4 |
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