PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells

Oncogenic protein kinase C epsilon (PKCε) promotes the formation of membrane ruffles and motility in non-small cell lung cancer (NSCLC) cells. We found that PKCε is down-regulated when NSCLC cells undergo epithelial-to-mesenchymal transition (EMT) in response to TGF-β, thus becoming dispensable for...

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Dettagli Bibliografici
Pubblicato in:Small GTPases
Autori principali: Cooke, Mariana, Baker, Martin J., Kazanietz, Marcelo G., Casado-Medrano, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939553/
https://ncbi.nlm.nih.gov/pubmed/31648598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2019.1684785
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