The Notch Signaling Inhibitor DAPT Downregulates Cdk5 Activity and Modulates the Distribution of Neuronal Cytoskeletal Proteins

Por Kanungo, Jyotshnabala, Zheng, Yali, Amin, Niranjana D., Pant, Harish C.
Publicado em 2008

Targeting Cdk5 Activity in Neuronal Degeneration and Regeneration

Por Kanungo, Jyotshnabala, Zheng, Ya-li, Amin, Niranjana D., Pant, Harish C.
Publicado no Cell Mol Neurobiol (2009)

Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation

Por Sharma, Pushkar, Sharma, Monica, Amin, Niranjana D., Albers, R. Wayne, Pant, Harish C.
Publicado em 1999

Pin1-dependent Prolyl Isomerization Modulates the Stress-induced Phosphorylation of High Molecular Weight Neurofilament Protein

Por Rudrabhatla, Parvathi, Zheng, Ya-Li, Amin, Niranjana D., Kesavapany, Sashi, Albers, Wayne, Pant, Harish C.
Publicado em 2008

Specific Inhibition of Cyclin-dependent Kinase 5 Activity Induces Motor Neuron Development in vivo

Por Kanungo, Jyotshnabala, Zheng, Ya-Li, Amin, Niranjana D., Kaur, Sukhbir, Ramchandran, Ramani, Pant, Harish C.
Publicado em 2009

TFP5, a Peptide Derived from p35, a Cdk5 Neuronal Activator, Rescues Cortical Neurons from Glucose Toxicity

Por Binukumar, BK, Zheng, Ya-Li, Shukla, Varsha, Amin, Niranjana D., Grant, Philip, Pant, Harish C.
Publicado no J Alzheimers Dis (2014)

Cdk5 Modulation of Mitogen-activated Protein Kinase Signaling Regulates Neuronal Survival

Por Zheng, Ya-Li, Li, Bing-Sheng, Kanungo, Jyotshna, Kesavapany, Sashi, Amin, Niranjana, Grant, Philip, Pant, Harish C.
Publicado em 2007

Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation

Por Lee, Myoung-Hwa, Amin, Niranjana D., Venkatesan, Arun, Wang, Tongguang, Tyagi, Richa, Pant, Harish C., Nath, Avindra
Publicado em 2013

Activation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia

Por Prochazkova, Michaela, Terse, Anita, Amin, Niranjana D, Hall, Bradford, Utreras, Elias, Pant, Harish C, Kulkarni, Ashok B
Publicado em 2013

Cyclin-Dependent Kinase 5 Modulates the Transcriptional Activity of the Mineralocorticoid Receptor and Regulates Expression of Brain-Derived Neurotrophic Factor

Por Kino, Tomoshige, Jaffe, Howard, Amin, Niranjana D., Chakrabarti, Mayukh, Zheng, Ya-Li, Chrousos, George P., Pant, Harish C.
Publicado em 2010

Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson’s disease

Por Binukumar, BK., Shukla, Varsha, Amin, Niranjana D., Grant, Philip, Bhaskar, M., Skuntz, Susan, Steiner, Joseph, Pant, Harish C.
Publicado no Mol Biol Cell (2015)

A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons

Por Zheng, Ya-Li, Kesavapany, Sashi, Gravell, Maneth, Hamilton, Rebecca S, Schubert, Manfred, Amin, Niranjana, Albers, Wayne, Grant, Philip, Pant, Harish C
Publicado em 2005

A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice

Por Shukla, Varsha, Zheng, Ya-Li, Mishra, Santosh K., Amin, Niranjana D., Steiner, Joseph, Grant, Philip, Kesavapany, Sashi, Pant, Harish C.
Publicado em 2013

The interaction of Munc 18 (p67) with the p10 domain of p35 protects in vivo Cdk5/p35 activity from inhibition by TFP5, a peptide derived from p35

Por Amin, Niranjana D., Zheng, Yali, BK, Binukumar, Shukla, Varsha, Skuntz, Susan, Grant, Philip, Steiner, Joseph, Bhaskar, Manju, Pant, Harish C.
Publicado no Mol Biol Cell (2016)

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

Por Veeranna, Yang, Dun-Sheng, Lee, Ju-Hyun, Vinod, K. Yaragudri, Stavrides, Philip, Amin, Niranjana D., Pant, Harish C., Nixon, Ralph A.
Publicado em 2009

Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway

Por Demelash, Abeba, Rudrabhatla, Parvathi, Pant, Harish C., Wang, Xiaoyang, Amin, Niranjana D., McWhite, Claire D., Naizhen, Xu, Linnoila, R. Ilona
Publicado em 2012

Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein

Por Binukumar, B.K., Shukla, Varsha, Amin, Niranjana D., Bhaskar, Manju, Skuntz, Suzanne, Steiner, Joseph, Winkler, Dirk, Pelech, Steven L., Pant, Harish C.
Publicado no J Alzheimers Dis (2015)

Peripheral and orofacial pain sensation is unaffected by the loss of p39

Por Prochazkova, Michaela, Hall, Bradford, Hu, Minghan, Okine, Tracy, Reukauf, Jennifer, Binukumar, BK, Amin, Niranjana D, Roque, Eva, Pant, Harish C, Kulkarni, Ashok B
Publicado no Mol Pain (2017)

A 24-Residue Peptide (p5), Derived from p35, the Cdk5 Neuronal Activator, Specifically Inhibits Cdk5-p25 Hyperactivity and Tau Hyperphosphorylation

Por Zheng, Ya-Li, Amin, Niranjana D., Hu, Ya-Fang, Rudrabhatla, Parvathi, Shukla, Varsha, Kanungo, Jyotshnabala, Kesavapany, Sashi, Grant, Philip, Albers, Wayne, Pant, Harish C.
Publicado em 2010

NEUROFILAMENT TAIL PHOSPHORYLATION: IDENTITY OF THE RT97 PHOSPHOEPITOPE AND REGULATION IN NEURONS BY CROSSTALK AMONG PROLINE-DIRECTED KINASES

Por Veeranna, Lee, Ju-Hyun, Pareek, Tej K., Jaffee, Howard, Boland, Barry, Vinod, K. Yaragudri, Amin, Niranjana, Kulkarni, Ashok B., Pant, Harish C., Nixon, Ralph A.
Publicado em 2008