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TFP5, a Peptide Derived from p35, a Cdk5 Neuronal Activator, Rescues Cortical Neurons from Glucose Toxicity

Multiple lines of evidence link the incidence of diabetes to the development of Alzheimer’s disease (AD). Patients with diabetes have a 50 to 75% increased risk of developing AD. Cyclin dependent kinase 5 (Cdk5) is a serine/threonine protein kinase, which forms active complexes with p35 or p39, foun...

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Bibliografske podrobnosti
izdano v:J Alzheimers Dis
Main Authors: Binukumar, BK, Zheng, Ya-Li, Shukla, Varsha, Amin, Niranjana D., Grant, Philip, Pant, Harish C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578662/
https://ncbi.nlm.nih.gov/pubmed/24326517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-131784
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