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The Notch Signaling Inhibitor DAPT Downregulates Cdk5 Activity and Modulates the Distribution of Neuronal Cytoskeletal Proteins

Notch signaling is critical for the development of the nervous system. Cdk5 is a neuronal kinase involved in neuronal development and phosphorylates a number of neuronal cytoskeletal proteins. To determine the relationship between Notch and cdk5 signaling, we tested the effects of the Notch inhibito...

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Detalhes bibliográficos
Main Authors: Kanungo, Jyotshnabala, Zheng, Yali, Amin, Niranjana D., Pant, Harish C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631422/
https://ncbi.nlm.nih.gov/pubmed/18662245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05551.x
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