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The Notch Signaling Inhibitor DAPT Downregulates Cdk5 Activity and Modulates the Distribution of Neuronal Cytoskeletal Proteins
Notch signaling is critical for the development of the nervous system. Cdk5 is a neuronal kinase involved in neuronal development and phosphorylates a number of neuronal cytoskeletal proteins. To determine the relationship between Notch and cdk5 signaling, we tested the effects of the Notch inhibito...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631422/ https://ncbi.nlm.nih.gov/pubmed/18662245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05551.x |
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