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Specific Inhibition of Cyclin-dependent Kinase 5 Activity Induces Motor Neuron Development in vivo
Cyclin-dependent kinase 5 (cdk5) is a ubiquitous protein activated by specific activators, p35 and p39. Cdk5 regulates neuronal migration, differentiation, axonogenesis, synaptic transmission and apoptosis. However, its role in motor neuron development remains unexplored. Here, using gain and loss-o...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758157/ https://ncbi.nlm.nih.gov/pubmed/19523926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.038 |
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