Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG)

Autor Harp, Joel M., Coates, Leighton, Sullivan, Brendan, Egli, Martin
Vydáno v Acta Crystallogr F Struct Biol Commun (2018)

Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography

Autor Harp, Joel M, Coates, Leighton, Sullivan, Brendan, Egli, Martin
Vydáno v Nucleic Acids Res (2021)

Structure of the heterodimeric ecdysone receptor DNA-binding complex

Autor Devarakonda, Srikripa, Harp, Joel M., Kim, Youngchang, Ożyhar, Andrzej, Rastinejad, Fraydoon
Vydáno 2003

Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time

Autor Leuba, Sanford H., Anand, Syam P., Harp, Joel M., Khan, Saleem A.
Vydáno 2008

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine

Autor Su, Yan, Patra, Amritraj, Harp, Joel M., Egli, Martin, Guengerich, F. Peter
Vydáno v J Biol Chem (2015)

Computational design of an endo-1,4-β-xylanase ligand binding site

Autor Morin, Andrew, Kaufmann, Kristian W., Fortenberry, Carie, Harp, Joel M., Mizoue, Laura S., Meiler, Jens
Vydáno 2011

Analysis of the Structure and Function of YfcG from Escherichia coli Reveals an Efficient and Unique Disulfide Bond Reductase,

Autor Wadington, Megan C., Ladner, Jane E., Stourman, Nina V., Harp, Joel M., Armstrong, Richard N.
Vydáno 2009

Total Synthesis of Stemaphylline N-oxide and Related C9a-Epimeric Analogs

Autor Schulte, Michael L., Turlington, Mark L., Phatak, Sharangdhar S., Harp, Joel M., Stauffer, Shaun R., Lindsley, Craig W.
Vydáno 2013

Structure and Function of YghU, A Nu-class Glutathione Transferase Related to YfcG from Escherichia coli,

Autor Stourman, Nina V., Branch, Megan C., Schaab, Matthew R., Harp, Joel M., Ladner, Jane E., Armstrong, Richard N.
Vydáno 2011

Molecular Basis for Cyclooxygenase Inhibition by the Non-steroidal Anti-inflammatory Drug Naproxen

Autor Duggan, Kelsey C., Walters, Matthew J., Musee, Joel, Harp, Joel M., Kiefer, James R., Oates, John A., Marnett, Lawrence J.
Vydáno 2010

Evaluation of TSPO PET Ligands [(18)F]VUIIS1009A and [(18)F]VUIIS1009B: Tracers for Cancer Imaging

Autor Tang, Dewei, Li, Jun, Buck, Jason R., Tantawy, Mohamed Noor, Xia, Yan, Harp, Joel M., Nickels, Michael L., Meiler, Jens, Manning, H. Charles
Vydáno v Mol Imaging Biol (2017)

Synthesis and Structure-Activity Relationships of 5,6,7-substituted Pyrazolopyrimidines: Discovery of a novel TSPO PET Ligand for Cancer Imaging

Autor Tang, Dewei, McKinley, Eliot T., Hight, Matthew R., Uddin, Md. Imam, Harp, Joel M., Fu, Allie, Nickels, Michael L., Buck, Jason R., Manning, H. Charles
Vydáno 2013

Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections

Autor Lepesheva, Galina I., Park, Hee-Won, Hargrove, Tatiana Y., Vanhollebeke, Benoit, Wawrzak, Zdzislaw, Harp, Joel M., Sundaramoorthy, Munirathinam, Nes, W. David, Pays, Etienne, Chaudhuri, Minu, Villalta, Fernando, Waterman, Michael R.
Vydáno 2010

Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity

Autor Harp, Joel M, Guenther, Dale C, Bisbe, Anna, Perkins, Lydia, Matsuda, Shigeo, Bommineni, Gopal R, Zlatev, Ivan, Foster, Donald J, Taneja, Nate, Charisse, Klaus, Maier, Martin A, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Egli, Martin
Vydáno v Nucleic Acids Res (2018)

Discovery of the first M(5)-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-...

Autor Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Kett, Nathan R., Harp, Joel M., Cho, Hyekyung P., Smith, Emery, Chase, Peter, Hodder, Peter S., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Wood, Michael R., Lindsley, Craig W.
Vydáno 2013

Discovery of VU6005649, a CNS Penetrant mGlu(7/8) Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines

Autor Abe, Masahito, Seto, Mabel, Gogliotti, Rocco G., Loch, Matthew T., Bollinger, Katrina A., Chang, Sichen, Engelberg, Eileen M., Luscombe, Vincent B., Harp, Joel M., Bubser, Michael, Engers, Darren W., Jones, Carrie K., Rodriguez, Alice L., Blobaum, Anna L., Conn, P. Jeffrey, Niswender, Colleen M., Lindsley, Craig W.
Vydáno v ACS Med Chem Lett (2017)

A Novel M(1) PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity

Autor Rook, Jerri M., Bertron, Jeanette L., Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Moran, Sean P., Maksymetz, James T., Nance, Kellie D., Dickerson, Jonathan W., Remke, Daniel H., Chang, Sichen, Harp, Joel M., Blobaum, Anna L., Niswender, Colleen M., Jones, Carrie K., Stauffer, Shaun R., Conn, P. Jeffrey, Lindsley, Craig W.
Vydáno v ACS Chem Neurosci (2018)