Probing the Role of HDACs and Mechanisms of Chromatin-Mediated Neuroplasticity

מאת Haggarty, Stephen J., Tsai, Li-Huei
יצא לאור 2011

Translation: Screening for Novel Therapeutics Using Disease-Relevant Cell Types Derived from Human Stem Cell Models

מאת Haggarty, Stephen J., Perlis, Roy H.
יצא לאור 2013

Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies

מאת Silva, M. Catarina, Haggarty, Stephen J.
הוצא לאור ב Int J Mol Sci (2020)

Human Pluripotent Stem Cell-Derived Models and Drug Screening in CNS Precision Medicine

מאת Silva, M. Catarina, Haggarty, Stephen J.
הוצא לאור ב Ann N Y Acad Sci (2019)

Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: Past, present, and future

מאת Alural, Begum, Genc, Sermin, Haggarty, Stephen J.
הוצא לאור ב Prog Neuropsychopharmacol Biol Psychiatry (2016)

Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch

מאת Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
הוצא לאור ב J Biol Chem (2016)

Toward Development of Epigenetic Drugs for CNS Disorders: Modulating Neuroplasticity via H3K4 Methylation

מאת Ricq, Emily L., Hooker, Jacob M., Haggarty, Stephen J.
הוצא לאור ב Psychiatry Clin Neurosci (2016)

SpectralNET – an application for spectral graph analysis and visualization

מאת Forman, Joshua J, Clemons, Paul A, Schreiber, Stuart L, Haggarty, Stephen J
יצא לאור 2005

Epigenetic Mechanisms in Mood Disorders: Targeting Neuroplasticity

מאת Fass, Daniel M., Schroeder, Frederick A., Perlis, Roy H., Haggarty, Stephen J.
יצא לאור 2013

Advancing Drug Discovery for Neuropsychiatric Disorders Using Patient-Specific Stem Cell Models

מאת Haggarty, Stephen J., Silva, M. Catarina, Cross, Alan, Brandon, Nicholas J., Perlis, Roy H.
הוצא לאור ב Mol Cell Neurosci (2016)

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

מאת Haggarty, Stephen J., Koeller, Kathryn M., Wong, Jason C., Grozinger, Christina M., Schreiber, Stuart L.
יצא לאור 2003

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

מאת Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
הוצא לאור ב Curr Protoc Hum Genet (2017)

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells

מאת Iaconelli, Jonathan, Lalonde, Jasmin, Watmuff, Bradley, Liu, Bangyan, Mazitschek, Ralph, Haggarty, Stephen J., Karmacharya, Rakesh
הוצא לאור ב ACS Chem Biol (2017)

Chemical Genetics Identifies Small-Molecule Modulators of Neuritogenesis Involving Neuregulin-1/ErbB4 Signaling

מאת Kuai, Letian, Wang, Xiang, Madison, Jon M., Schreiber, Stuart L., Scolnick, Edward M., Haggarty, Stephen J.
יצא לאור 2010

Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

מאת Samara, Chrysanthi, Rohde, Christopher B., Gilleland, Cody L., Norton, Stephanie, Haggarty, Stephen J., Yanik, Mehmet Fatih
יצא לאור 2010

Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

מאת Moreno-Yruela, Carlos, Fass, Daniel M., Cheng, Chialin, Herz, Joachim, Olsen, Christian A., Haggarty, Stephen J.
הוצא לאור ב ACS Chem Neurosci (2019)

A High-Throughput Screen for Wnt/β-catenin Signaling Pathway Modulators in Human iPSC-derived Neural Progenitors

מאת Zhao, Wen-Ning, Cheng, Chialin, Theriault, Kraig M., Sheridan, Steven D., Tsai, Li-Huei, Haggarty, Stephen J.
יצא לאור 2012

Chemical Phylogenetics of Histone Deacetylases

מאת Bradner, James E., West, Nathan, Grachan, Melissa L., Greenberg, Edward F., Haggarty, Stephen J., Warnow, Tandy, Mazitschek, Ralph
יצא לאור 2010

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

מאת Huang, Jing, Zhu, Heng, Haggarty, Stephen J., Spring, David R., Hwang, Heejun, Jin, Fulai, Snyder, Michael, Schreiber, Stuart L.
יצא לאור 2004

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

מאת Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
יצא לאור 2010