Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

Por Singh, Melissa M., Manton, Christa A., Bhat, Krishna P., Tsai, Wen-Wei, Aldape, Kenneth, Barton, Michelle C., Chandra, Joya
Publicado em 2011

Targeting intercellular adhesion molecule-1 prolongs survival in mice bearing bevacizumab-resistant glioblastoma

Por Piao, Yuji, Henry, Verlene, Tiao, Ningyi, Park, Soon Young, Martinez-Ledesma, Juan, Dong, Jian Wen, Balasubramaniyan, Veerakumar, de Groot, John F.
Publicado no Oncotarget (2017)

Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity

Por Qin, Na, Han, Fengli, Li, Li, Ge, Yingwei, Lin, Wei, Wang, Jiang, Wu, Lin, Zhao, Gang, Deng, Yanchun, Zhang, Jian
Publicado no Oncol Lett (2019)

Comparison of Hospitals Affiliated With PPS-Exempt Cancer Centers, Other Hospitals Affiliated With NCI-Designated Cancer Centers, and Other Hospitals That Provide Cancer Care

Por Merkow, Ryan P., Yang, Anthony D., Pavey, Emily, Song, Min-Woong, Chung, Jeanette W., Bentrem, David J., Bilimoria, Karl Y.
Publicado no JAMA Intern Med (2019)

Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells

Por Ryeong-Eun Kim, Chan Young Shin, Seol-Heui Han, Kyoung Ja Kwon
Publicado em 2020-09-01

DIPG-15. EFFECTIVE PRECLINICAL TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA BY MELK INHIBITION

Por Meel, Michaël H, Guillén-Navarro, Miriam, de Gooijer, Mark C, Waranecki, Piotr, Buijl, Levi CM, van Tellingen, Olaf, van Vuurden, Dannis G, Kaspers, Gertjan JL, Hulleman, Esther
Publicado no Neuro Oncol (2017)

Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in m...

Por Mengmeng Li, Chenli Li, Hanjie Yu, Xiongxiong Cai, Xinbei Shen, Xin Sun, Jinting Wang, Yanhua Zhang, Chuang Wang
Publicado em 2017-09-01

Activation of p53 by Nutlin-3a Induces Apoptosis and Cellular Senescence in Human Glioblastoma Multiforme

Por Villalonga-Planells, Ruth, Coll-Mulet, Llorenç, Martínez-Soler, Fina, Castaño, Esther, Acebes, Juan-Jose, Giménez-Bonafé, Pepita, Gil, Joan, Tortosa, Avelina
Publicado em 2011

HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND

Por Jin, Jingji, Lam, Lucy, Sadic, Edin, Fernandez, Frank, Tan, Jun, Giunta, Brian
Publicado em 2012

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

Por Chantong Boonrat, Kratschmar Denise V, Nashev Lyubomir G, Balazs Zoltan, Odermatt Alex
Publicado em 2012-11-01

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

Por Chantong, Boonrat, Kratschmar, Denise V, Nashev, Lyubomir G, Balazs, Zoltan, Odermatt, Alex
Publicado em 2012

P11.08 Systematic drug repurposing for faster cures of pediatric cancer identifies that Digoxin prolongs survival in a PDOX model of group 4 medulloblastoma

Por Huang, L., Injac, S. G., Zhao, H., Lin, Q., Kogiso, M., Man, C., Li, X., Lau, C., Wong, S. T. C.
Publicado no Neuro Oncol (2017)

Rcor2 underexpression in senescent mice: a target for inflammaging?

Por Alvarez-López, María J, Molina-Martínez, Patricia, Castro-Freire, Marco, Cosín-Tomás, Marta, Cristòfol, Rosa, Párrizas, Marcelina, Escorihuela, Rosa María, Pallàs, Merce, Sanfeliu, Coral, Kaliman, Perla
Publicado em 2014

ξUp-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an <it>in vivo </it>and <it>in vitro </it>study

Por Wang Hung-Li, Ro Long-Sun, Lin Ya-Tin, Chen Jin-Chung
Publicado em 2011-09-01

Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer

Por Van Swearingen, Amanda E D, Sambade, Maria J, Siegel, Marni B, Sud, Shivani, McNeill, Robert S, Bevill, Samantha M, Chen, Xin, Bash, Ryan E, Mounsey, Louisa, Golitz, Brian T, Santos, Charlene, Deal, Allison, Parker, Joel S, Rashid, Naim, Miller, C Ryan, Johnson, Gary L, Anders, Carey K
Publicado no Neuro Oncol (2017)

Intermedin(1–53) Protects Against Myocardial Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Inflammation Induced by Homocysteine in Apolipoprotein E-Deficient Mice

Por Zhang, Jin-Sheng, Hou, Yue-Long, Lu, Wei-Wei, Ni, Xian-Qiang, Lin, Fan, Yu, Yan-Rong, Tang, Chao-Shu, Qi, Yong-Fen
Publicado no J Atheroscler Thromb (2016)

Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus

Por Yang, Jing, Liu, Rongjun, Lu, Fan, Xu, Fang, Zheng, Jinwei, Li, Zhao, Cui, Wei, Wang, Chuang, Zhang, Junfang, Xu, Shujun, Zhou, Wenhua, Wang, Qinwen, Chen, Junping, Chen, Xiaowei
Publicado no Front Pharmacol (2019)

Effects of Aliskiren on Stroke in Rats Expressing Human Renin and Angiotensinogen Genes

Por Schmerbach, Kristin, Pfab, Thiemo, Zhao, Yi, Culman, Juraj, Mueller, Susanne, Villringer, Arno, Muller, Dominik N., Hocher, Berthold, Unger, Thomas, Thoene-Reineke, Christa
Publicado em 2010

Antidepressant-Like Effects of Gyejibokryeong-hwan in a Mouse Model of Reserpine-Induced Depression

Por Park, Bo-Kyung, Kim, Yu Ri, Kim, Young Hwa, Yang, Changsop, Seo, Chang-Seob, Jung, In Chul, Jang, Ik-Soon, Kim, Seung-Hyung, Lee, Mi Young
Publicado no Biomed Res Int (2018)

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

Por Kool, Marcel, Koster, Jan, Bunt, Jens, Hasselt, Nancy E., Lakeman, Arjan, van Sluis, Peter, Troost, Dirk, Meeteren, Netteke Schouten-van, Caron, Huib N., Cloos, Jacqueline, Mršić, Alan, Ylstra, Bauke, Grajkowska, Wieslawa, Hartmann, Wolfgang, Pietsch, Torsten, Ellison, David, Clifford, Steven C., Versteeg, Rogier
Publicado em 2008