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Activation of p53 by Nutlin-3a Induces Apoptosis and Cellular Senescence in Human Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. Despite concerted efforts to improve current therapies and develop novel clinical approaches, patient survival remains poor. As such, increasing attention has focused on developing new therapeutic strategi...

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Detalhes bibliográficos
Main Authors: Villalonga-Planells, Ruth, Coll-Mulet, Llorenç, Martínez-Soler, Fina, Castaño, Esther, Acebes, Juan-Jose, Giménez-Bonafé, Pepita, Gil, Joan, Tortosa, Avelina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071734/
https://ncbi.nlm.nih.gov/pubmed/21483692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018588
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