Targeting intercellular adhesion molecule-1 prolongs survival in mice bearing bevacizumab-resistant glioblastoma

Intercellular cell adhesion molecule 1 (ICAM-1; also known as CD54) is overexpressed in bevacizumab-resistant glioblastoma. In the present study, we tested our hypothesis that highly expressed ICAM-1 mediates glioblastoma’s resistance to antiangiogenic therapy. We validated ICAM-1 overexpression in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Piao, Yuji, Henry, Verlene, Tiao, Ningyi, Park, Soon Young, Martinez-Ledesma, Juan, Dong, Jian Wen, Balasubramaniyan, Veerakumar, de Groot, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722538/
https://ncbi.nlm.nih.gov/pubmed/29228586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18859
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