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DRES-09. THERAPEUTIC TARGETING OF CLK2 AND PI3K/mTOR IN GLIOBLASTOMA STEM CELLS
Key signaling genes of the PI3K pathway are mutated in a large proportion of human glioblastoma (GBM), leading to persistent activation of the pathway. To determine the efficacy of inhibiting multiple components or the RTK/PI3K pathway, we examined GSK2126458 (PI3K/mTOR inhibitor) in a panel of glio...
में बचाया:
| में प्रकाशित: | Neuro Oncol |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692817/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.267 |
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