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DR-08 MSK1/ β-CATENIN SIGNALING MEDIATES RESISTANCE TO PI3K/mTOR INHIBITORS IN GLIOBLASTOMA

Glioblastoma, with aberrant activation of growth factor signaling pathways, represents a compelling disease for kinase inhibitor therapy. Despite the evidence defining the PI3K network as a high quality target, regulatory feedback loops as well as cross-talk with other networks make understanding an...

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Detalhes bibliográficos
Main Authors: Wu, Shaofang, Zheng, Siyuan, Verhaak, Roel, Koul, Dimpy, Yung, W. K. Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218047/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou252.8
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