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DR-08 MSK1/ β-CATENIN SIGNALING MEDIATES RESISTANCE TO PI3K/mTOR INHIBITORS IN GLIOBLASTOMA
Glioblastoma, with aberrant activation of growth factor signaling pathways, represents a compelling disease for kinase inhibitor therapy. Despite the evidence defining the PI3K network as a high quality target, regulatory feedback loops as well as cross-talk with other networks make understanding an...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218047/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou252.8 |
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