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Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

Glioblastoma multiforme (GBM) is a particularly aggressive brain tumor and remains a clinically devastating disease. Despite innovative therapies for the treatment of GBM, there has been no significant increase in patient survival over the past decade. Enzymes that control epigenetic alterations are...

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Detalhes bibliográficos
Main Authors: Singh, Melissa M., Manton, Christa A., Bhat, Krishna P., Tsai, Wen-Wei, Aldape, Kenneth, Barton, Michelle C., Chandra, Joya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145466/
https://ncbi.nlm.nih.gov/pubmed/21653597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor049
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