THER-31. TARGETING THE HISTONE DEMETHYLASE LSD1 FOR SELECTIVE APOPTOSIS AND IMMUNE-SENSITIZATION IN PEDIATRIC DIPG

Pediatric midline gliomas, mainly DIPGs, are a rare and deadly cancer of early childhood, with a 9-month median survival post-diagnosis and a 2-year survival rate of <10%. Their growth on the brainstem makes surgical resection nearly impossible and radiation is primarily palliative. Epigenetic th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bailey, Cavan, Kennis, Bridget, Romero, Megan, Han, Ruolan, Larson, Jeffrey, Becher, Oren, Monje, Michelle, Gopalakrishnan, Vidya, Zaky, Wafik, Lee, Dean, Chandra, Joya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477272/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.236
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