EXTH-67. PHARMACOLOGIC INHIBITION OF LYSINE SPECIFIC DEMETHYLASE-1 (LSD1) AS AN ADJUVANT IMMUNE-SENSITIZATION STRATEGY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Diffuse midline gliomas (DMG), including brainstem DIPG (diffuse intrinsic pontine glioma), are incurable pediatric brain tumors. Mutations in the H3 histone tail (H3.1/3.3-K27M) are a feature of DIPG, highlighting epigenetic aberrations in these tumors. Lysine specific demethylase-1 (LSD1), is an e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Bailey, Cavan, Collier, Tiara, Henry, Verlene, Monje, Michelle, Nazarian, Javad, Lee, Dean, Wang, Linghua, Gopalakrishnan, Vidya, Becher, Oren, Chandra, Joya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Preclinical Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651117/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.421
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia