Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive form of brain cancer. Our previous studies demonstrated that combined inhibition of HDAC and KDM1A increases apoptotic cell death in vitro. However, whether this combination also increases death of the glioma stem cell (GSC) population...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Singh, Melissa M., Johnson, Blake, Venkatarayan, Avinashnarayan, Flores, Elsa R., Zhang, Jianping, Su, Xiaoping, Barton, Michelle, Lang, Frederick, Chandra, Joya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Basic and Translational Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648298/
https://ncbi.nlm.nih.gov/pubmed/25795306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov041
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