Effects of Aliskiren on Stroke in Rats Expressing Human Renin and Angiotensinogen Genes

OBJECTIVE: Pre-treatment with angiotensin receptor blockers is known to improve neurological outcome after stroke. This study investigated for the first time, whether the renin inhibitor aliskiren has similar neuroprotective effects. METHODS: Since aliskiren specifically blocks human renin, double t...

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Detalhes bibliográficos
Main Authors: Schmerbach, Kristin, Pfab, Thiemo, Zhao, Yi, Culman, Juraj, Mueller, Susanne, Villringer, Arno, Muller, Dominik N., Hocher, Berthold, Unger, Thomas, Thoene-Reineke, Christa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993950/
https://ncbi.nlm.nih.gov/pubmed/21124781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015052
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