Resultados da pesquisa - (( j l comps can newts ) OR ((( 3 nar (camp OR com) c new ) OR ( a brain colas carlos negron ))))

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Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease

Por Xu, Shuang-yong, Gupta, Yogesh K.
Publicado em 2013

“...-Asn-His and a zinc-binding site [CxxC](2). An additional zinc ribbon (ZR) domain with one to two zinc...”
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Reconstructing spatial organizations of chromosomes through manifold learning

Por Zhu, Guangxiang, Deng, Wenxuan, Hu, Hailin, Ma, Rui, Zhang, Sai, Yang, Jinglin, Peng, Jian, Kaplan, Tommy, Zeng, Jianyang
Publicado no Nucleic Acids Res (2018)

“... manner and provide new insights into the folding of three-dimensional (3D) genome structure...”
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DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences

Por Laughlin-Toth, Sarah, Carter, E. Kathleen, Ivanov, Ivaylo, Wilson, W. David
Publicado no Nucleic Acids Res (2017)

“... both A·T and G·C base pairs, we recently discovered that the heterocyclic diamidine, DB2277, forms a...”
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Inferential modeling of 3D chromatin structure

Por Wang, Siyu, Xu, Jinbo, Zeng, Jianyang
Publicado no Nucleic Acids Res (2015)

“... of the genome. In this paper, we develop a new Bayesian framework to derive the 3D architecture of a chromosome...”
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Recent updates and developments to plant genome size databases

Por Garcia, Sònia, Leitch, Ilia J., Anadon-Rosell, Alba, Canela, Miguel Á., Gálvez, Francisco, Garnatje, Teresa, Gras, Airy, Hidalgo, Oriane, Johnston, Emmeline, Mas de Xaxars, Gemma, Pellicer, Jaume, Siljak-Yakovlev, Sonja, Vallès, Joan, Vitales, Daniel, Bennett, Michael D.
Publicado em 2014

“... and (iii) a webpage containing information about flow cytometry protocols....”
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Bisulfighter: accurate detection of methylated cytosines and differentially methylated regions

Por Saito, Yutaka, Tsuji, Junko, Mituyama, Toutai
Publicado em 2014

“..., we present Bisulfighter, a new software package for detecting mCs and DMRs from bisulfite sequencing...”
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Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine

Por Zhao, Chao, Wang, Hailin, Zhao, Bailin, Li, Cuiping, Yin, Ruichuan, Song, Maoyong, Liu, Baodong, Liu, Zhen, Jiang, Guibin
Publicado em 2014

“... (BA) can inhibit the amplification activity of Taq DNA polymerase for replicating glucosylated 5hmC...”
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A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia

Por Ali, Aamir, Veeranki, Sailaja Naga, Tyagi, Shweta
Publicado em 2014

“...MLL, the trithorax ortholog, is a well-characterized histone 3 lysine 4 methyltransferase...”
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Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation

Por Ahmed, Tofayel, Shi, Jian, Bhushan, Shashi
Publicado no Nucleic Acids Res (2017)

“..., except for a new bridge involving uL2c and bS6c....”
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Partial bisulfite conversion for unique template sequencing

Por Kumar, Vijay, Rosenbaum, Julie, Wang, Zihua, Forcier, Talitha, Ronemus, Michael, Wigler, Michael, Levy, Dan
Publicado no Nucleic Acids Res (2018)

“...We introduce a new protocol, mutational sequencing or muSeq, which uses sodium bisulfite...”
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ADAR mediates differential expression of polycistronic microRNAs

Por Chawla, Geetanjali, Sokol, Nicholas S.
Publicado em 2014

“...-Complex (let-7-C) locus. For example, a single A-to-I change at the −6 residue of pri-miR-100, the first...”
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ChIP-seq reveals the global regulator AlgR mediating cyclic di-GMP synthesis in Pseudomonas aeruginosa

Por Kong, Weina, Zhao, Jingru, Kang, Huaping, Zhu, Miao, Zhou, Tianhong, Deng, Xin, Liang, Haihua
Publicado no Nucleic Acids Res (2015)

“... messenger cyclic diguanylate (c-di-GMP). A ΔalgR strain produced lesser biofilm than did the wild-type...”
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Enzymatic synthesis of cyclic dinucleotide analogs by a promiscuous cyclic-AMP-GMP synthetase and analysis of cyclic dinucleotide responsive riboswitches

Por Launer-Felty, Katherine D, Strobel, Scott A
Publicado no Nucleic Acids Res (2018)

“..., production of some of these analogs involves lengthy, multistep syntheses. Here, we describe a new, simple...”
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Structure of mycobacterial 3′-to-5′ RNA:DNA helicase Lhr bound to a ssDNA tracking strand...

Por Ejaz, Anam, Ordonez, Heather, Jacewicz, Agata, Ferrao, Ryan, Shuman, Stewart
Publicado no Nucleic Acids Res (2018)

“... helix (WH) domain and a unique C-terminal domain. The 3′ ssDNA end binds in a crescent-shaped groove...”
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PABP enhances release factor recruitment and stop codon recognition during translation termination

Por Ivanov, Alexandr, Mikhailova, Tatyana, Eliseev, Boris, Yeramala, Lahari, Sokolova, Elizaveta, Susorov, Denis, Shuvalov, Alexey, Schaffitzel, Christiane, Alkalaeva, Elena
Publicado no Nucleic Acids Res (2016)

“... by recruitment of eRF3a and eRF1 to the ribosome. PABP's function in translation termination depends on its C...”
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Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background

Por Weuts, An, Voet, Thierry, Verbeeck, Jelle, Lambrechts, Nathalie, Wirix, Evelyne, Schoonjans, Luc, Danloy, Sophie, Marynen, Peter, Froyen, Guy
Publicado em 2012

“... Linear Human Artificial Chromosome (L-HAC) as a new tool for telomere studies. The L-HAC was generated...”
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Mechanistic insights from the crystal structures of a feast/famine regulatory protein from Mycobacterium tuberculosis H37Rv

Por Shrivastava, Tripti, Ramachandran, Ravishankar
Publicado em 2007

“...Rv3291c gene from Mycobacterium tuberculosis codes for a transcriptional regulator belonging...”
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An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

Por Fine, Eli J., Cradick, Thomas J., Zhao, Charles L., Lin, Yanni, Bao, Gang
Publicado em 2014

“... by predicting 44 of 65 previously confirmed off-target sites, and by uncovering a new off-target site...”
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A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation

Por Dronamraju, Raghuvar, Strahl, Brian D.
Publicado em 2014

“..., these results elucidate a new control mechanism for the regulation of RNAPII CTD phosphorylation during...”
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Elongator-dependent modification of cytoplasmic tRNA(Lys)(UUU) is required for mitochondrial function under stress conditions

Por Tigano, Marco, Ruotolo, Roberta, Dallabona, Cristina, Fontanesi, Flavia, Barrientos, Antoni, Donnini, Claudia, Ottonello, Simone
Publicado no Nucleic Acids Res (2015)

“... in Saccharomyces cerevisiae. We identified 105 new genes whose deletion impairs respiratory growth at 37°C...”
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