Reconstructing spatial organizations of chromosomes through manifold learning

Decoding the spatial organizations of chromosomes has crucial implications for studying eukaryotic gene regulation. Recently, chromosomal conformation capture based technologies, such as Hi-C, have been widely used to uncover the interaction frequencies of genomic loci in a high-throughput and genom...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Zhu, Guangxiang, Deng, Wenxuan, Hu, Hailin, Ma, Rui, Zhang, Sai, Yang, Jinglin, Peng, Jian, Kaplan, Tommy, Zeng, Jianyang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934626/
https://ncbi.nlm.nih.gov/pubmed/29408992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky065
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