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Reconstructing spatial organizations of chromosomes through manifold learning

Decoding the spatial organizations of chromosomes has crucial implications for studying eukaryotic gene regulation. Recently, chromosomal conformation capture based technologies, such as Hi-C, have been widely used to uncover the interaction frequencies of genomic loci in a high-throughput and genom...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhu, Guangxiang, Deng, Wenxuan, Hu, Hailin, Ma, Rui, Zhang, Sai, Yang, Jinglin, Peng, Jian, Kaplan, Tommy, Zeng, Jianyang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934626/
https://ncbi.nlm.nih.gov/pubmed/29408992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky065
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