Reconstructing spatial organizations of chromosomes through manifold learning

Decoding the spatial organizations of chromosomes has crucial implications for studying eukaryotic gene regulation. Recently, chromosomal conformation capture based technologies, such as Hi-C, have been widely used to uncover the interaction frequencies of genomic loci in a high-throughput and genom...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Zhu, Guangxiang, Deng, Wenxuan, Hu, Hailin, Ma, Rui, Zhang, Sai, Yang, Jinglin, Peng, Jian, Kaplan, Tommy, Zeng, Jianyang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934626/
https://ncbi.nlm.nih.gov/pubmed/29408992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky065
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