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Elongator-dependent modification of cytoplasmic tRNA(Lys)(UUU) is required for mitochondrial function under stress conditions

To gain a wider view of the pathways that regulate mitochondrial function, we combined the effect of heat stress on respiratory capacity with the discovery potential of a genome-wide screen in Saccharomyces cerevisiae. We identified 105 new genes whose deletion impairs respiratory growth at 37°C by...

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Publicat a:Nucleic Acids Res
Autors principals: Tigano, Marco, Ruotolo, Roberta, Dallabona, Cristina, Fontanesi, Flavia, Barrientos, Antoni, Donnini, Claudia, Ottonello, Simone
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787798/
https://ncbi.nlm.nih.gov/pubmed/26240381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv765
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