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Structure of mycobacterial 3′-to-5′ RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases

Mycobacterial Lhr is a DNA damage-inducible superfamily 2 helicase that uses adenosine triphosphate (ATP) hydrolysis to drive unidirectional 3′-to-5′ translocation along single-stranded DNA (ssDNA) and to unwind RNA:DNA duplexes en route. ATPase, translocase and helicase activities are encompassed w...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ejaz, Anam, Ordonez, Heather, Jacewicz, Agata, Ferrao, Ryan, Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758891/
https://ncbi.nlm.nih.gov/pubmed/29165676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1163
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