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Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

Replication protein A (RPA) is the main eukaryotic ssDNA-binding protein with essential roles in DNA replication, recombination, and repair. RPA maintains the DNA as single-stranded and also interacts with other DNA-processing proteins, coordinating their assembly and disassembly on DNA. RPA binds t...

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Detalhes bibliográficos
Main Authors: Fan, Jie, Pavletich, Nikola P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475805/
https://ncbi.nlm.nih.gov/pubmed/23070815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.194787.112
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