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BLM SUMOylation regulates ssDNA accumulation at stalled replication forks
Polymerase stalling results in uncoupling of DNA polymerase and the replicative helicase, which generates single-stranded DNA (ssDNA). After stalling, RAD51 accumulates at stalled replication forks to stabilize the fork and to repair by homologous recombination (HR) double-strand breaks (DSBs) that...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761158/ https://ncbi.nlm.nih.gov/pubmed/24027577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00167 |
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