BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

Diverse functions, including DNA replication, recombination and repair, occur during S phase of the eukaryotic cell cycle. It has been proposed that p53 and BLM help regulate these functions. We show that p53 and BLM accumulated after hydroxyurea (HU) treatment, and physically associated and co-loca...

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Autors principals: Sengupta, Sagar, Linke, Steven P., Pedeux, Remy, Yang, Qin, Farnsworth, Julie, Garfield, Susan H., Valerie, Kristoffer, Shay, Jerry W., Ellis, Nathan A., Wasylyk, Bohdan, Harris, Curtis C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150347/
https://ncbi.nlm.nih.gov/pubmed/12606585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg114
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